![]() Additional randomized trials could change these findings. This indicates that there is considerable uncertainty regarding the effect of HFO on death. This is because of a lack of precision and consistency, and because in many cases the methods used by investigators during clinical trials were not of the highest standard. The quality of evidence is very low for outcomes that would be most important to patients. space tracking purpose, in medical devices and in the measuring instruments. We found substantial inconsistency among clinical trials which reported the effect of HFO on the risk of death in participants with ARDS. This article discusses about what is a crystal oscillator, quartz crystal. The risk of unwanted side effects, including low blood pressure or further injury to the lung due to high airway pressure, was not increased. HFO had no effect on the length of time an artificial breathing machine was required. The ability of the lungs to oxygenate blood, measured at 24 to 72 hours of ventilation after randomization, was 18% to 26% better in participants receiving HFO. HFO did not reduce the risk of death in hospital in eight trials enrolling 1779 participants. Four trials reported at least some funding from manufacturers of HFO ventilators. One large trial was stopped early because of increased deaths among participants who were randomized to HFO. We included 10 randomized controlled trials (RCTs) enrolling 1850 participants in this updated review. We performed a systematic review to determine whether HFO improves clinical outcomes (including preventing deaths) when compared to conventional breathing machines for adults and children with ARDS. HFO helps with the opening of collapsed lung tissue by providing constant positive pressure in a person's airway. High-frequency oscillation (HFO) ventilation differs from conventional ventilation in that very small breaths are delivered very rapidly (180 to 900 breaths per minute). ![]() People with ARDS usually require an artificial respirator in order to prevent death. Survivors can have a reduced quality of life. It is characterized by acute lung inflammation, stiff lungs that increase the work of breathing, and reduced ability of the lungs to adequately oxygenate the blood. Acute respiratory distress syndrome (ARDS) is a life-threatening condition.
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